Green synthesis of SeNPs using Sonchus maritimus based nanosized metal oxides for in vitro biological applications and in vivo acute toxicity evaluation

This investigation aimed to characterize the green synthesized selenium nanoparticles using Sonchus maritimus L. extract and evaluate their antioxidant antibacterial properties. Moreover, acute toxicity of was performed in Wistar rats. The synthesis SeNPs confirmed by Ultraviolet-visible, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy Energy Dispersive X-ray analysis. Antioxidant activities S. SmE-SeNPs were determined DPPH FRAP assays. Antibacterial tested against Gram positive negative pathogen bacteria. SEM results showed that had a spherule-like structure reaching up 26.48 nm. In addition, scavenging activity reducing power. exhibited Escherichia coli Staphylococcus aureus. intraperitoneal test no mortality minor behavioral variations. conclusion, can be considered as biocatalyst stabilizers for biosynthesis which might used several applications due biological efficiency.